When staying in Arequipa and you want to go to canyon colca, it might be better to book a room in Chivay for two nights. Then you can go to see the condors early in the morning (around 7) and afterwards you can continue the road to a next busstop where you can go all the way down into the canyon. Beware also that it takes at least 4 hours to make the way back up so I your still in it, wait for some local people to join then or make your way on a donkey. From chivay you can't take a direct bus to puno but you can take it partways and then jump on the one which comes from arequipa to save you some more hours. When it's full, for a few dollars you can have the place next to the driver which gives you some really marvellous views on the straight roads in front of you on the altiplano.